Mapping the Brain-Wide Cholinergic Neurons Projecting to Skeletal Muscle in Mice by High-Throughput Light Sheet Tomography

作     者：Dayu Chen Xiaofeng Cheng Xiong Yang Yongsheng Zhang Zhigang He Qian Wang Guojie Yao Xiuli Liu Shaoqun Zeng Jincao Chen Hongbing Xiang Dayu Chen;Xiaofeng Cheng;Xiong Yang;Yongsheng Zhang;Zhigang He;Qian Wang;Guojie Yao;Xiuli Liu;Shaoqun Zeng;Jincao Chen;Hongbing Xiang

作者机构：Department of NeurosurgeryZhongnan Hospital of Wuhan UniversityWuhan 430071China Department of NeurosurgeryCentral Theater Command General Hospital of the People’s Liberation ArmyWuhan 430070China Britton Chance Center for Biomedical PhotonicsWuhan National Laboratory for OptoelectronicsHuazhong University of Science and TechnologyWuhan 430074China Ministry of Education Key Laboratory for Biomedical PhotonicsSchool of Engineering SciencesHuazhong University of Science and TechnologyWuhan 430074China Department of Emergency MedicineTongji Hospital of Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074China Department of Anesthesiology and Pain MedicineTongji Hospital of Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China 

出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)

年 卷 期：2021年第37卷第2期

页      面：267-270页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071006[理学-神经生物学] 

基　　金：This work was supported by grants from the Foundation of Health and Family Planning Commission of Hubei Province,China(WJ2018H0074) the National Natural Science Foundation of China(61721092,81670240 and 81873467) 

主　　题：skeletal muscles cholinergic 

摘      要：Dear Editor,The cholinergic system plays an important role in regulating locomotion and motor functions by modulating neuronal activity[1].However,the anatomical relationships between the brain-wide cholinergic system and skeletal muscles remain *** understand how this system modulates the activity of skeletal muscles,details of the pattern of cholinergic innervation and differences in the innervation of skeletal muscles are ***,classical immunohistochemical methods are unable to test unequivocally whether a mapping exists in the connections from the brain to skeletal muscles.