The miR156/SPL Module, a Regulatory Hub and Versatile Toolbox, Gears up Crops for Enhanced Agronomic Traits

作     者：Hai Wang Haiyang Wang 

作者机构：Biotechnology Research Institute Chinese Academy of Agricultural Sciences Beijing 100081 China 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2015年第8卷第5期

页      面：677-688页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 0828[工学-农业工程] 08[工学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 0713[理学-生态学] 

基　　金：supported by National Science Foundation of China (NSFC) project to Haiyang Wang 

主　　题：agronomic trait crop miR156 SQUAMOSA-PROMOTER BINDING PROTEIN-LIKE (SPL) 

摘      要：In the past two decades, members of the SQUAMOSA-PROMOTER BINDING PROTEIN-LIKE （SPL） family of transcription factors, first identified in Antirrhinum majus, have emerged as pivotal regulators of diverse biological processes in plants, including the timing of vegetative and reproductive phase change, leaf development, tillering/branching, plastochron, panicle/tassel architecture, fruit ripening, fertility, and response to stresses. Transcripts of a subset of SPLs are targeted for cleavage and/or translational repres- sion by microRNA156s （miR156s）. The levels of miR156s are regulated by both endogenous developmental cues and various external stimuli. Accumulating evidence shows that the regulatory circuit around the miR156/SPL module is highly conserved among phylogenetically distinct plant species, and plays impor- tant roles in regulating plant fitness, biomass, and yield. With the expanding knowledge and a mechanistic understanding of their roles and regulatory relationship, we can now harness the miR156/SPL module as a plethora of tools to genetically manipulate crops for optimal parameters in growth and development, and ultimately to maximize yield by intelligent design of crops.