Effect of MTECl on the functional expression of TCRαβ^+3G11^-6C10^-CD4^+CD8^- thymocyte subset

作     者：GE Qing and CHEN WeifengDepartment of Immunology, Beijing Medical University, Beijing 100083, China Corresponding author 

出 版 物：《Chinese Science Bulletin》 (科学通报(英文版))

年 卷 期：1999年第44卷第17期

页      面：1571-1576页

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学] 

主　　题：TCRαβ⁺3G11^-6C10^-CD4⁺ CD8⁺ CD69^+/- HSA^med/lo thymocyte subset thymic stromal cells cytokine 

摘      要：A murine CD4+ thymocyte subset with phenotype of TCRαβ + 3G11- 6C10- CD4 + CD8- CD69 + /- HSAmed/lo contains the cells in relatively functional matured status. The functional property of the cells in this subset is characterized by the unique pattern of cytokine production at transitional stage from ThO to Th2 type with the latter being the dominant type. After being co-cultured with murine thymic medullary epithelial cell line (MTEC1) cells, a murine