Long-term outcomes of penetrating keratoplasty in keratoconus: analysis of the factors associated with final visual acuities

作     者：Jin A Choi Min A Lee Man-Soo Kim 

作者机构：Department of Ophthalmology St. Vincent's HospitalCollege of Medicine the Catholic University of Korea #93 Jungbudae-ro Paldal-gu Suwon-si Kyunggi-do 442-723Korea Department of Ophthalmology and Visual Science Seoul St.Mary's Hospital College of Medicine Catholic University of Korea #505 Banpo-dong Seocho-ku Seoul 137-701 Korea 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2014年第7卷第3期

页      面：517-521页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：keratoconus penetrating keratoplasty visual outcome 

摘      要：AIM:To investigate the long-term results of penetrating keratoplasty(PK)in patients with keratoconus(KC)and to evaluate factors that might influence the final visual ***:We retrospectively reviewed the data of all patients with clinical KC who had undergone PK by a single corneal surgeon in a single center from May 1980to December *** age of the patients,preoperative best-corrected visual acuity(BCVA),corneal thickness,death to preservation time,and preservation to transplantation time were ***,postoperative complications such as graft rejection,development of glaucoma and specular microscopy were checked during the ***:Sixty-nineeyesfrom69patientswerefinally *** follow-up period was 8.64±*** rejection occurred in 4 eyes of 69 cases(5.8%),and the time to graft rejection was 2.1±1.3y.A Kaplan-Meier survival analysis showed that the estimated cumulative probability of graft rejection at 6,13,and 17y after PK were 95.6%,90.0%,and 78.8%,*** we evaluated factors that might influence final BCVA in eyes,no disparity donor-host trephine size(same graft size)as well as higher spherical equivalent,and average Kvalue were associated with higher final BCVA.(P=0.006,0.051,0.092,and 0.021 in eyes with follow-up8y;P=0.068,0.065,and 0.030 in eyes with follow-up≥8y,respectively).CONCLUSION:The long-term results of PK in patients with KC were favorable with a high percentage of good *** myopic change and low average K-reading,as well as a surgical technique using the same size donor-recipient button may provide better visual outcomes particularly in patients with KC.