The Chromosome-Level Genome Sequence of the Autotetraploid Alfalfa and Resequencing of Core Germplasms Provide Genomic Resources for Alfalfa Research

作     者：Chen Shen Huilong Du Zhuo Chen Hongwei Lu Fugui Zhu Hong Chen Xiangzhao Meng Qianwen Liu Peng Liu Lihua Zheng Xiuxiu Li Jiangli Dong Chengzhi Liang Tao Wang Chen Shen;Huilong DU;Zhuo Chen;Hongwei Lu;Fugui Zhu;Hong Chen;Xiangzhao Meng;Qianwen Liu;Peng Liu;Lihua Zheng;Xiuxiu Li;Jiangli Dong;Chengzhi Liang;Tao Wang

作者机构：State Key Laboratory of AgrobiotechnologyCollege of Biological SciencesChina Agricultural UniversityBeijingChina State Key Laboratory of Plant GenomicsInstitute of Genetics and Developmental BiologyInnovation Academy for Seed DesignChinese Academy of SciencesBeijingChina University of Chinese Academy of SciencesBeijingChina 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2020年第13卷第9期

页      面：1250-1261页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

基　　金：supported by the National Key Research&Development Program of China(2019YFD1002701) Agricultural Variety Improvemnt Project of Shandong Province(2019LZGC010) the Project for Extramural Scientists of the State Key Laboratory for Agrobiotech no logy(2020SKLAB6-15,2011SKLAB01-1) 

主　　题：alfalfa genome assembly population gen etics GW AS Flowering Locus T 

摘      要：Alfalfa(Medicago sativa)is one of the most important forage crops in the world;however,its molecular genetics and breeding research are hindered due to the lack of a high-quality reference ***,we report a de novo assembled 816-Mb high-quality,chromosome-level haploid genome sequence for‘Zhongmu No.1’alfalfa,a heterozygous *** contig N50 is 3.92 Mb,and 49165 genes are annotated in the *** alfalfa genome is estimated to have diverged from *** approximately 8 million years *** population analysis of 162 alfalfa accessions revealed high genetic diversity,weak population structure,and extensive gene flow from wild to cultivated ***-wide association studies identified many candidate genes associated with important agronomic ***,we showed that MsFTa2,a Flowering Locus T homolog,whose expression is upregulated in salt-resistant germplasms,may be associated with fall dormancy and salt *** together,these genomic resources will facilitate alfalfa genetic research and agronomic improvement.