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Histone variant H2A.Z facilitates DNA replication

Histone variant H2A.Z facilitates DNA replication

作     者:Lei Qiu Xinyi Zeng Junhong Han Lei Qiu;Xinyi Zeng;Junhong Han

作者机构:Department of Abdominal OncologyState Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan Universityand Collaborative Innovation Center for BiotherapyChengdu 610041China 

出 版 物:《Science China(Life Sciences)》 (中国科学(生命科学英文版))

年 卷 期:2020年第63卷第5期

页      面:788-790页

核心收录:

学科分类:0710[理学-生物学] 0830[工学-环境科学与工程(可授工学、理学、农学学位)] 07[理学] 071007[理学-遗传学] 

基  金:supported by the National Natural Science Foundation of China(31972884) 1·3·5 Project for Disciplines of Excellence,West China Hospital(ZYGD18003),Sichuan University。 

主  题:structure. H2A.Z DNA 

摘      要:In eukaryotes,DNA wraps around the histone octamer to form nucleosomes,which are further compacted into the chromosome structure.The chromosome contains multiple replication origins that are regulated by both DNA sequence and epigenetic features.

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