Gut inflammation in the pathogenesis of acquired aplastic anemia

作     者：Xi-Chen Zhao Xiao-Yun Sun Li Zhao Fan-Jun Meng Zhao Xi-Chen;Sun Xiao-Yun;Zhao Li;Meng Fan-Jun

作者机构：Department of HematologyThe Central Hospital of Qingdao West Coast New AreaQingdaoShandong 266555China Department of HematologyThe Affiliated Hospital of Qingdao UniversityQingdaoShandong 266000China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2020年第133卷第15期

页      面：1878-1881页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：inflammation anemia aplastic 

摘      要：Acquired aplastic anemia(AAA)is an auto-immune disease(AID)resulting from aberrant T-cell-mediated and antigen-driven immune responses to hematopoietic stem and progenitor cells(HSPCs)in genetically susceptible individuals,leading to the significantly enhanced suppression and apoptosis of *** systemic and local inflammation is responsible for the overall pathophysiology.