Crystal structure of the African swine fever virus structural protein p35 reveals its role for core shell assembly

作     者：Guobang Li Dan Fu Guangshun Zhang Dongming Zhao Mingyu Li Xue Geng Dongdong Sun Yuhui Wang Cheng Chen Peng Jiao Lin Cao Yu Guo Zihe Rao Guobang Li;Dan Fu;Guangshun Zhang;Dongming Zhao;Mingyu Li;Xue Geng;Dongdong Sun;Yuhui Wang;Cheng Chen;Peng Jiao;Lin Cao;Yu Guo;Zihe Rao

作者机构：State Key Laboratory of Medicinal Chemical Biology and College of PharmacyNankai UniversityTianjin 300350China State Key Laboratory of Veterinary BiotechnologyHarbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150001China School of Life SciencesTianjin UniversityTianjin 300071China 

出 版 物：《Protein & Cell》 (蛋白质与细胞（英文版）)

年 卷 期：2020年第11卷第8期

页      面：600-605页

核心收录：

学科分类：090601[农学-基础兽医学] 09[农学] 0906[农学-兽医学] 

基　　金：supported by grants from the National Key R&D Program of China 国家自然科学基金 国家自然科学基金 Young Elite Scientist Sponsorship Program by CAST Science and Technology Innovation Achievements and Team Building Foundation of Nankai University 

主　　题：swine fever African 

摘      要：Dear Editor,The African swine fever(ASF)is a highly contagious hemorrhagic and lethal disease in domestic *** ASF outbreaks of in many Asia countries,including China,Vietnam,Mongolia,and South Korea,have posed a huge threat to the pig *** the attempt to stop ASF from spreading further in China s Mainland,more than 10 million pigs have been culled since August *** causative agent for ASF is a DNA virus,African swine fever virus(ASFV).Although this deadly disease has been reported in Kenya nearly one hundred years ago,there has been no vaccine for protection from ASFV infection or effective treatments to cure ASF until now.