Detection of Polymorphism of Pituitary Specific Transcription Factor 1 Gene and Its Association with Bodyweight of Fulani and Yoruba Ecotype Chickens
Detection of Polymorphism of Pituitary Specific Transcription Factor 1 Gene and Its Association with Bodyweight of Fulani and Yoruba Ecotype Chickens作者机构：Department of Animal Science University of Ibadan Ibadan Nigeria Department of Animal Genetics Breeding and Reproduction College of Animal Science South China Department of Animal Science Shanghai Jiao Tong University Shanghai People’s Republic of China School of Chemistry and Molecular Bioscience University of Queensland Brisbane Queensland Australia
出 版 物：《Open Journal of Animal Sciences》 (动物科学期刊（英文）)
年 卷 期：2020年第10卷第2期
页 面：278-286页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：PIT-1 Gene Polymorphism Chicken
摘 要：Pituitary Specific transcription factor 1 (PIT-1) gene is one of the POU gene family and play key roles in the regulation of muscle development which is important for body weight in chickens. This study was carried out to detect the polymorphism of PIT-1 gene and study its association with body weight in Fulani and Yoruba ecotype of Nigerian indigenous chickens. A total of 100 day-old chicks comprising of fifty chicks of Fulani and Yoruba ecotypes were used for this study. These chicks were genotyped using PCR-RFLP technique and their growth rate was also measured throughout the study. Our results showed two alleles A and B controlling genotypes AA and AB which were significantly associated with bodyweight of the chickens. Interestingly, we found out that AA genotype had the highest frequency of 0.64 and 0.76 compared with AB genotype which had a frequency of 0.36 and 0.24 in the Fulani and Yoruba ecotype respectively. Furthermore, the PIT-1 genotypes (AA and AB) were significantly associated (p 0.05) with body weight at week 4 and week 12 in Fulani and Yoruba ecotype chicken respectively. PIT-1 gene was polymorphic in Fulani and Yoruba ecotypes of Nigeria Indigenous Chickens.
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