Combining the Patient-Generated Subjective Global Assessment (PGSGA) and Objective Nutrition Assessment Parameters Better Predicts Malnutrition in Elderly Patients with Colorectal Cancer

作     者：Wen Jun Wang Ting Ting Li Xu Wang Wei Li Jiu Wei Cui Wen Jun Wang;Ting Ting Li;Xu Wang;Wei Li;Jiu Wei Cui

作者机构：Cancer CenterFirst Hospital of Jilin UniversityJilin UniversityChangchunJilin130021China 

出 版 物：《Journal of Nutritional Oncology》 (肿瘤营养学杂志（英文）)

年 卷 期：2020年第5卷第1期

页      面：22-30页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：the Project of Health and Family Planning Commission of Jilin Province(Grant 2017J064 to JW.C) the Project of Jilin Provincial Department of Education(Grant JJKH20190020KJ to JW.C) 

主　　题：Colorectal cancer Elderly patients Malnutrition Bioelectrical impedance analysis Scored patientgenerated subjective global assessment 

摘      要：Background Malnutrition is common in colorectal cancer(CRC)patients,especially in elderly *** Patient-Generated Subjective Global Assessment(PG-SGA)is a widely used tool developed to detect *** aim of this study was to compare the value of the PG-SGA and objective nutrition assessment parameters,in order to identify a better predictive index for malnutrition in elderly patients with *** A total of 131 elderly patients(age≥60 years)with CRC were included and were evaluated for their individual nutritional status using the *** and serological indicators were also assayed within 48 h of admission to the *** composition analysis was implemented by bioelectrical impedance analysis(BIA)*** Chi-squared test,univariate and multivariate logistic regression analysis,or Spearman’s rank correlation analysis were used to determine the differences among the above indices and parameters with regard to predicting *** According to the PG-SGA score,the incidence of total malnutrition in elderly patients with CRC was 80.92%(PG-SGA score≥2),which increased with *** was found that 28%of the patients with PG-SGA classification A(PG-SGA score 0-1)had a low fat-free mass index(FFMI).Compared with those with PG-SGA A,patients with PG-SGA C PG-SGA score≥9)showed an increased neutrophil to lymphocyte ratio(NLR)and an increased platelet and lymphocyte ratio(PLR)(median=1.78 VS.2.35,P=0.015 and median=108.8 VS.141.6,P=0.001,respectively).In terms of objective nutrition assessment parameters,severely malnourished CRC patients had significantly lower values of serum albumin(ALB),and retinol conjugated protein(RBP)than those who were well-nourished[(38.35±4.84)g/L VS.(40.56±3.44)g/L,P=0.039 and(30.31±15.83)mg/L VS.(39.01±11.95)mg/L,P=0.033,respectively].The Spearman’s rank correlation analysis showed that the PG-SGA findings had positive correlations with the NLR and PLR;while it had negative correlations with