5-year efficacy of all surface laser ablation with cross-linking(ASLA-XTRA)for the treatment of myopia

作     者：Ioannis M.Aslanides Farhad Hafezi Shihao Chen Hatch Mukherjee Vasileios Selimis Ilias Maragkos Nanji Lu George Kymionis 

作者机构：Emmetropia Mediterranean Eye InstitutePlateia Eleftherias 44Heraklion71201 CreteGreece Eye HospitalWenzhou Medical UniversityWenzhouChina Center for Applied Biotechnology and Molecular MedicineUniversity of ZurichDietikon/ZurichSwitzerland ELZA InstituteDietikon/ZurichSwitzerland USC Roski Eye InstituteUniversity of Southern CaliforniaCaliforniaLos AngelesUSA Faculty of MedicineUniversity of GenevaGenevaSwitzerland Essex County HospitalEssexUK Athens Medical SchoolUniversity of AthensAthensGreece Faculty of Biology and MedicineJules Gonin Eye HospitalUniversity of LausanneLausanneSwitzerland 

出 版 物：《Eye and Vision》 (眼视光学杂志（英文）)

年 卷 期：2020年第7卷第1期

页      面：294-299页

核心收录：

学科分类：1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

主　　题：Refractive surgery Transepithelial PRK ASLA Cross-linking CXL ASLA-XTRA 

摘      要：Background:The purpose of our study is to examine the long(5-year)efficacy of the all surface laser ablation(ASLA)combined with accelerated cross-linking(CXL)for the treatment of myopia without the use of mitomycin-C(MMC).Methods:This retrospective study consisted of 202 eyes of 118 myopic(SD:2.41,range:−1.50 to−12.75 D)patients(44 males,74 females).Mean age was 28.50 years(SD:6.45,range:18 to 51 years)that underwent ASLA with accelerated CXL for the treatment of their ***:The patients underwent routine postoperative assessment on the 1st,3rd,7th day and in the 1st,3rd,6th and 12th month,30th month(±6 months),4th and 5th *** mean spherical equivalent(SEq)refractive error changed from−6.41±2.41 D preoperatively to−0.02±0.53 D at 5 years *** haze score was 0.18,0.25 and 0.28 at 1,3 and 6 months *** 12 months after the treatment,no eyes had significant corneal haze and in all the following postoperative time intervals the haze traces were ***:ASLA combined with accelerated CXL(ASLA-XTRA)appears to be safe,efficacious and offering very good refractive *** potential additional benefits of this modality are the stabilizing effect of the refraction and its sterilization effect on the treated cornea without the potential side effects of MMC.