Multifunctions of Histone H1 Proteins

作     者：WANG Wenjun CAI Ruiqi XIAO Hongdou ZHENG Ling 

作者机构：College of Life Sciences Wuhan University Diabetes Center Wuhan University 

出 版 物：《Wuhan University Journal of Natural Sciences》 (武汉大学学报（自然科学英文版）)

年 卷 期：2014年第19卷第1期

页      面：8-18页

学科分类：0710[理学-生物学] 07[理学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

基　　金：Supported by the National Basic Research Program of China(2012CB524901) the Natural Science Foundation of China(31271370,81100687) the Program for New Century Excellent Talents in University(NECT10-0623) 

主　　题：histone H1 proteins posttranslational modifications gene transcription cell cycle 

摘      要：Among various histones, histone H1 proteins have been appreciated for their multiple functions in diverse biological processes. In addition to being a structural protein in chromatin, H1 proteins also play critical roles in cell cycle, gene expression, and development. Recent studies reveal the possible effects of H1 in some diseases, such as cancer and neurodegenerative diseases. Here, we review different variants of HI, the functions, and post translational modifications of ill variants are also discussed.