Environmental and biological influences on the stability of silver nanoparticles

作     者：LIU Wei ZHOU QunFang LIU JiYan FU JianJie LIU SiJin JIANG GuiBin 

作者机构：State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-environmental Sciences Chinese Academy ofSciences Beijing 100085 China 

出 版 物：《Chinese Science Bulletin》 (Chin. Sci. Bull.)

年 卷 期：2011年第56卷第19期

页      面：2009-2015页

核心收录：

学科分类：07[理学] 070205[理学-凝聚态物理] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0702[理学-物理学] 

基　　金：supported by the National Basic Research Program of China (2009CB421605) the National Natural Science Foundation of China (B20977100) the Knowledge Innovation Program of the Chinese Academy of Sciences (KZCX2-YW-420-21) 

主　　题：银纳米粒子 生物因素 稳定性 环境 Zeta电位 离子强度 胎牛血清 DMEM 

摘      要：Silver nanoparticles (Ag NPs) are easily dispersed and stable, and their application has become widespread. Consequently, concern has arisen regarding their potential effects on the environment and human health. However, the current understanding on the stability of Ag NPs is limited. Therefore, in this study the influence of environmental and biological factors, such as ionic strength, valence, biological molecules, pH and temperature, on the properties of Ag NPs was investigated. The absorption spectra, size, zeta potential, and release of silver ions were evaluated. Ionic strength, valence, Dulbecco’s Modified Eagle’s Medium (DMEM), without fetal bovine serum (FBS), reduced the stability of the Ag NPs. However, in DMEM with 10% FBS, the Ag NPs maintained their stability and nanoscale characteristics. These findings provide an essential insight into the environmental and biological factors that should be evaluated in a risk assessment of Ag NPs.