同基因混合G-CSF动员的异基因骨髓移植物诱导的抗白血病效应(英文)

作     者：Yihong Huang Bing Du Kailin Xu Depeng Li Xupeng He Qunxian Lu Xiuying Pan 

作者机构：Department of Hematology The Affiliated Hospital Xuzhou Medical College Xuzhou 221002 China 

出 版 物：《The Chinese-German Journal of Clinical Oncology》 (中德临床肿瘤学杂志（英文版）)

年 卷 期：2008年第7卷第9期

页      面：549-554页

学科分类：0710[理学-生物学] 090603[农学-临床兽医学] 1002[医学-临床医学] 07[理学] 09[农学] 0906[农学-兽医学] 071002[理学-动物学] 

基　　金："Qing-Lan Project" of Education Department of Jiangsu Province (No. SJS200512) 

主　　题：鼠科动物 粒细胞刺激因子 移植物抗白血病 急性移植物抗宿主病 

摘      要：Objective: To study clinical characteristics of non-Hodgkin s lymphoma (NHL) in order to diagnose and treat early and improve prognosis. Methods: 112 cases with NHL were pathologically diagnosed and treated in 1992-2005. Results: Among all cases, 30 were not treated previously, 79 were involved in peripheral lymph nodes, 55 deep lymph nodes, 18 Waldeyer s ring, 25 respiratory system, 26 digestive system, 26 spleen, 13 bone, 13 skin and subcutaneous, 4 urinogenital system, 13 other sites. Among 30 previously untreated patients, there were 4 staged I, 3 IE, 5 II, 1 IIE, 9 III, 1 IIIS and 7 IV. Among 82 patients with prior treatment, 29 were involved in lymph nodes only, 53 involved in different organs and tissues. In our series, there were 38 cases and 74 cases belonged to subtype A and subtype B respectively. Conclusion: The enlargement of peripheral lymph nodes is main clinical characteristic in NHL, but lesions also involve different organs and tissues. The diagnosis of NHL depends upon pathological examination.