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Lipases catalyzed acetylation of meso-2,4-dimethyl-1,5-pentanediol and the synthesis of Prelog-Djerassi lactone

Lipases catalyzed acetylation of meso-2,4-dimethyl-1,5-pentanediol and the synthesis of Prelog-Djerassi lactone

作     者:LIN, GQ XU, WC 

作者机构:CHINESE ACAD SCISHANGHAI INST ORGAN CHEMSHANGHAI 200032PEOPLES R CHINA 

出 版 物:《Chinese Journal of Chemistry》 (中国化学(英文版))

年 卷 期:1995年第13卷第4期

页      面:380-384页

核心收录:

学科分类:081705[工学-工业催化] 08[工学] 0817[工学-化学工程与技术] 

基  金:Project supported by the National Natural Science Foundation of China 

主  题:LIPASE (2R,4S)-5-ACETOXY-2,4-DIMETHYL-PENTANOL PRELOG-DJERASSI LACTONE 

摘      要:Lipase catalyzed acetylation of 2 afforded 3 with the e.e. up to 98%. Utility of 3 was illustrated by the preparation of Prelog-Djerassi lactones 7a and 7b.

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