Tetrabromobisphenol A(TBBPA): A controversial environmental pollutant

作     者：Hui Zhou Nuoya Yin Francesco Faiola Hui Zhou;Nuoya Yin;Francesco Faiola

作者机构：State Key Laboratory of Environmental Chemistry and EcotoxicologyResearch Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China College of Resources and EnvironmentUniversity of Chinese Academy of SciencesBeijing 100049China 

出 版 物：《Journal of Environmental Sciences》 (环境科学学报（英文版）)

年 卷 期：2020年第32卷第11期

页      面：54-66页

核心收录：

学科分类：083002[工学-环境工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 08[工学] 09[农学] 0903[农学-农业资源与环境] 0713[理学-生态学] 

基　　金：supported by the National Natural Science Foun-dation of China(Nos.21707160 and 21876197) the Chinese Academy of Sciences(No.QYZDJ-SSW-DQC017) the K.C.Wong Education Foundation 

主　　题：Tetrabromobisphenol A(TBBPA) Developmental toxicity Endocrine disrupting chemicals(EDC) Hepatotoxicity Neurotoxicity 

摘      要：Tetrabromobisphenol A(TBBPA)is one of the most widely used brominated flame retardants and is extensively used in electronic equipment,furniture,plastics,and *** is frequently detected in water,soil,air,and organisms,including humans,and has raised concerns in the scientific community regarding its potential adverse health *** exposure to TBBPA is mainly via diet,respiration,and skin *** in vivo and in vitro studies based on animal and cell models have demonstrated that TBBPA can induce multifaceted effects in cells and animals,and potentially exert hepatic,renal,neural,cardiac,and reproductive ***,other reports have claimed that TBBPA might be a safe *** this review,we re-evaluated most of the published TBBPA toxicological assessments with the goal of reaching a conclusion about its potential *** concluded that,although low TBBPA exposure levels and rapid metabolism in humans may signify that TBBPA is a safe chemical for the general population,particular attention should be paid to the potential effects of TBBPA on early developmental stages.