Hydrogen generating patch improves skin cell viability,migration activity,and collagen expression

作     者：Marina Safonov Jing You Jihyung Lee Vladimir L.Safonov Diana Berman Donghui Zhu 

作者机构：H2 Universe LLCGranburyTX 76049USA Department of Biomedical EngineeringUniversity of North TexasDentonTX 76203USA Materials Science and EngineeringUniversity of North TexasDentonTX 76203USA Department of Biomedical EngineeringStony Brook UniversityStony BrookNY 11794 

出 版 物：《Engineered Regeneration》 (再生工程（英文）)

年 卷 期：2020年第1卷第1期

页      面：1-5页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：The author(s) declared that no grants were involved in supporting this work. This work was performed in part at the University of North Texas Materials Research Facility 

主　　题：Hydrogen Skin Cell Collagen Viability 

摘      要：Molecular hydrogen recently attracted lots of attention in biomedical community because of its abilities to mod-ulate signal transduction,protein phosphorylation,and gene expression that enable its anti-inflammatory,anti-allergy,and anti-apoptotic ***,controllable and local delivery of hydrogen molecules to tissues still remains ***,we propose a new method of delivering molecular hydrogen directly to human skin cells by designing a hydrogen-generating patch that releases hydrogen in surrounding environment as a product of chemical reaction of aluminum and carbon hydroxide in presence of *** show that in the pres-ence of molecular hydrogen the cells viability,expression of collagen,and migration efficiency of cells increase,thus suggesting that hydrogen can be used to promote better and faster healing of skin issues such as wounds and bruises.