Efficacy of concentrated growth factors combined with mineralized collagen on quality of life and bone reconstruction of guided bone regeneration

作     者：Yan Dai Xiao-Hui Han Li-Hua Hu Hai-Wei Wu Sheng-Yun Huang Yu-Peng Lu 

作者机构：Department of Oral and Maxillofacial SurgeryCentral Hospital of ZiboShandong UniversityZibo 255036China Department of Oral and Maxillofacial Surgery Department of ProsthodonticsShandong Provincial Hospital Affiliated to Shandong UniversityJinan 250021China Key Laboratory for Liquid-Solid Structural Evolution and Processing of MaterialsMinistry of EducationShandong UniversityJinan 250061China School of Materials Science and EngineeringShandong UniversityJinan 250061China 

出 版 物：《Regenerative Biomaterials》 (再生生物材料（英文版）)

年 卷 期：2020年第7卷第3期

页      面：313-320页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 0836[工学-生物工程] 

基　　金：funded by China Postdoctoral Science Foundation Grant(No.2019M652380) 

主　　题：concentrated growth factors mineralized collagen guided bone regeneration bone augmentation osseointegration 

摘      要：To evaluate the clinical efficacy of concentrated growth factors(CGFs)combined with mineralized collagen(MC)in guided bone regeneration(GBR).A retrospective study involving 29 patients treated with GBR technique,which was performed either CGF and MC complexes or MC *** were inserted simultaneously and cone-beam computed tomography was taken immediately,at 3 and 6 months *** were completed by all patients so as to evaluate the main symptoms and daily activities during the first week after *** outcomes of the two groups were statistically *** implants healed *** in both groups suffered from different levels of discomfort for the reason of swelling,pain and chewing impairment on 1-2 ***,swelling of the Trial group was weaker than the Control *** compared with the Control group,pain levels in Trial group were more rapidly reduced and patients took fewer analgesics from Day ***,the reconstitution mean value of the graft was thicker at 3 and 6 months in Trial *** complex with MC were beneficial to relieve the clinical symptoms,promote the peri-implant bone regeneration and shorten the healing time.