成人红皮病:80例病例报道

作     者：Rym B.M Mourad M Bechir Z 焦婷 

作者机构：Dermatology Department La Rabta Hospital 1007 Rue Jabbari Bab Sadoun Tunis Tunisia.Dr 

出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)

年 卷 期：2006年第2卷第1期

页      面：3-3页

学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学] 

主　　题：红皮病 银屑病 特应性皮炎 药物反应 嗜伊红细胞增多 治疗资料 非特异性改变 性别比 西方国家 

摘      要：Background: Erythroderma is a generalized erythema of the skin accompanied by a variable degree of scaling. However, most of the published series originate fr om Western countries. There is only one report from Africa, conducted in Dakar i n 1979. The aim of our study was to provide information about this condition in our country. Patients and methods: Our study was retrospective, dealing with 80 erythrodermic adults, examined between January 1981 and December 2000. Patient i nformation included clinical, laboratory, histopathologic and therapeutic data. We also noted patientsoutcomes within an average follow-up period of 30 month s. Thus,we calculated the mortality rate and estimated the probability of surviv al without relapses according to the Kaplan-Meier method. Results: The frequenc y of erythroderma in our dermatology department was 0.3%. The sex ratio (male/f emale) was 2.2. The average age of our patients was 53.78 ±18 years. Previous h istory of skin disease was found in 49/80 patients (61.2%) and 32 of them were suffering from psoriasis. Hyperthermia was significantly associated with drug re actions (P=0.013). Hypereosinophilia was not a specific finding. The mortality r ate was higher than that of an age-matched population. Conclusion: Adult erythr oderma is a rare condition. Its most common cause in our study was psoriasis. No cases of atopic dermatitis were found. Prognosis was adversely affected by the presence of erythroderma.