Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty:a fellow-eye comparison

作     者：Rita Mencucci Eleonora Favuzza Elisa Marziali Michela Cennamo Cosimo Mazzotta Ersilia Lucenteforte Gianni Virgili Stanislao Rizzo Rita Mencucci;Eleonora Favuzza;Elisa Marziali;Michela Cennamo;Cosimo Mazzotta;Ersilia Lucenteforte;Gianni Virgili;Stanislao Rizzo

作者机构：Eye ClinicDepartment of NeurosciencePsychologyPharmacology and Child Health(NEUROFARBA)University of FlorenceEye ClinicLargo Brambilla 350134 FlorenceItaly Department of MedicineSurgery and NeurosciencesOphthalmology UnitSiena UniversitySienaItaly Siena Crosslinking CenterSienaItaly Department of Clinical and Experimental medicineUniversity of PisaPisaItaly 

出 版 物：《Eye and Vision》 (眼视光学杂志（英文）)

年 卷 期：2020年第7卷第1期

页      面：241-249页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：DMEK UT-DSAEK DSAEK Descemet stripping automated endothelial keratoplasty Ultra-thin Descemet stripping automated endothelial keratoplasty Descemet membrane endothelial keratoplasty 

摘      要：Background:To compare the visual outcome and patients’satisfaction after ultrathin Descemet stripping automated endothelial keratoplasty(UT-DSAEK)and Descemet membrane endothelial keratoplasty(DMEK)performed on fellow eyes of the same ***:In this retrospective study,the records of 18 pseudophakic patients affected by Fuchs endothelial dystrophy who underwent DMEK in one eye and UT-DSAEK in the fellow eye were *** corrected visual acuity(BCVA),corneal pachymetry,keratometry,corneal aberrations,photopic and mesopic contrast sensitivity,and endothelial cell counts measured 12 months after surgery in either eye were analyzed and *** results of a satisfaction questionnaire were also ***:Twelve months after surgery,BCVA was not significantly different in UT-DSAEK and DMEK eyes(0.10±0.04 and 0.07±0.07 logMAR,respectively);at both 4-and 6 mm optical zones total and posterior corneal higher order aberrations(HOAs),posterior astigmatism and total coma were significantly lower after DMEK;BCVA in both groups was significantly correlated mainly with anterior corneal aberrations;contrast sensitivity was higher after DMEK especially in mesopic conditions and at medium spatial frequencies;the endothelial cell density was similar,although slightly higher in the UT-DSAEK group(p=0.10).The satisfaction questionnaire showed that although patients were highly satisfied from both procedures,more than half of them preferred DMEK and reported a more comfortable and quicker postoperative ***:DMEK and UT-DSAEK showed no evidence of difference in terms of postoperative BCVA,although DMEK had a better performance in terms of contrast sensitivity,posterior corneal aberrations and overall patient satisfaction.