Changes of Immunoreactive β-Endorphin in Plasma, Pituitary and Hypothalamus of Rats during Oxygen-Induced Convulsions

作     者：陶恒沂 倪国坛 Tao Hengyi;Ni Guotan, Department of Diving Physiology, Faculty of Naval Medicine, Second Military Medical University, Shanghai

作者机构：Department of Diving Physiology Faculty of Naval Medicine Second Military Medical University Shanghai 

出 版 物：《Journal of Medical Colleges of PLA(China)》 (中国人民解放军军医大学学报（英文版）)

年 卷 期：1989年第4卷第1期

页      面：85-89页

学科分类：10[医学] 

主　　题：β-endorphin oxygen-induced convulsions naloxone radioimmunoassay antiserum rats 

摘      要：We observed for the first time the differences of immunoreactive β-endorphin(IR -β- EP) content in plasma, pituitary and hypothalamus of rats under various conditionsusing radioimmunoassay (RIA) and the effects of naloxone and β - endorphin (β- EP) antiserumon initial time of convulsions (ITC), severity of convulsions(SOC) and mortality on surface(MOS) of rats to hyperbaric oxygen(HBO). The results suggest thatβ- EP may partici-pate in the course of oxygen - induced convulsions and be one of endogenous convulsion - causingagents.