Coronavirus disease-2019: A tocsin to our aging, unfit, corpulent, and immunodeficient society

作     者：David C.Nieman David C. Nieman

作者机构：Department of BiologyCollege of Arts and SciencesAppalachian State UniversityNorth Carolina Research CampusKannapolisNC 28081USA 

出 版 物：《Journal of Sport and Health Science》 (运动与健康科学（英文）)

年 卷 期：2020年第9卷第4期

页      面：293-301页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：COVID-19 Exercise Immunology Infection Obesity 

摘      要：Acute and chronic respiratory illnesses cause widespread morbidity and mortality,and this class of illness now includes the novel coronavirus severe acute respiratory syndrome that is causing coronavirus disease-2019(COVID-19).The world is experiencing a major demographic shift toward an older,obese,and physically inactive *** factor assessments based on pandemic data indicate that those at higher risk for severe illness from COVID-19 include older males,and people of all ages with obesity and related comorbidities such as hypertension and type 2 *** in and of itself leads to negative changes in innate and adaptive immunity,a process termed *** causes systemic inflammation and adversely impacts immune function and host defense in a way that patterns *** primary prevention strategies to reduce the risk for COVID-19 at both the community and individual levels include mitigation activities and the adoption of lifestyle practices consistent with good immune *** and human studies support the idea that,in contrast to high exercise workloads,regular moderate-intensity physical activity improves immunosurveillance against pathogens and reduces morbidity and mortality from viral infection and respiratory illnesses including the common cold,pneumonia,and *** odds are high that infectious disease pandemics spawned by novel pathogens will continue to inflict morbidity and mortality as the world’s population becomes older and more ***-19 is indeed a wake-up call,a tocsin,to the world that primary prevention countermeasures focused on health behaviors and hygiene demand our full attention and support.