Prognosis in epithelial ovarian cancer: Clinical analysis of 287 pelvic and para-aortic lymphadenectomy
287例盆腔及腹主动脉旁淋巴结清扫术与卵巢上皮性癌生存预后的临床分析(英文)作者机构：Department of Obstetrics/Gynecology West China Second University Hospital Sichuan University Chengdu610041 China Department of Pathology West China Second University Hospital Sichuan University Chengdu 610041 China Department of Obstetrics/Gynecology The Second Teaching Hospital Sichuan University Chengdu 610041 China
出 版 物：《The Chinese-German Journal of Clinical Oncology》 (中德临床肿瘤学杂志（英文版）)
年 卷 期：2007年第6卷第5期
页 面：492-496页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：primary epithelial ovarian cancer systematic lymphadenectomy survival rate prognosis
摘 要：Objective: To evaluate the relationship between the pelvic and para-aortic lymphadenectomy and the prognosis of epithelial ovarian cancer. Methods: 287 patients suffering from primary epithelial ovarian cancer from 1995 to 2005 were analyzed retrospectively. Results: The 3-, 5-, 10-year survival with systematic lymphadenectomy (SL) were slightly higher than those without SL, but there were no statistically significance (P 0.05). The 3-, 5-, 10-year survival of clinical stages without SL were lower than those with SL, but there were no significant difference either (P 0.05). The 3-,5-, and 10-year survival rates with SL were higher than those without SL with no statistically differences (P 0.05) among the subgroups such as absent, ≤ 2 cm and 2 cm residual tumor. The survival rates of the groups without residual tumor and the group with ≤ 2 cm residual tumor were significantly higher than that of 2 cm (P 0.005). On multivariate analysis, patient staging (P = 0.01) and size of residual disease after primary cytoreductive surgery (P 0.001 and = 0.002, respectively) retained prognostic significance. SL was not proved to be an independent prognostic factor (P = 0.69). Conclusion: Systematic pelvic and para-aortic lymphadenectomy can not improve and prolong the survival time significantly.
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