黄斑裂孔术后视功能及主观视力知觉研究

作     者：Tranos P.G. Ghazi-Nouri S.M.S. Rubin G.S. 王海燕 

出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)

年 卷 期：2005年第1卷第5期

页      面：24-24页

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：黄斑裂孔 视功能 视物变形 手术干预 对比敏感度 简明健康调查表 功能恢复情况 临床数据 眼科研究所 系列分析 

摘      要：To evaluate the functional and anatomical results of macular hole surgery and to explore its effect on patients’Health-Related Quality Of Life (HR-QOL) and to investigate the associations between self-reported HR-QOL and conventional measures of visual function. Case series. The National Eye Institute 25-Item V isual Function Questionnaire (VFQ-25) and the 36-Item Short-Form Health Surve y (SF-36) were self-administered by 30 patients before and 4 months after macu lar hole surgery. Preoperative, intraoperative, and postoperative clinical data were collected including visual acuity, contrast sensitivity, and metamorphopsia . Multi-item scales rating different aspects of HR-QOL were compared before an d after surgery, and their correlation with traditional methods of outcome evalu ation was analyzed. Macular hole closure was achieved in 26 patients (87%). Mea n LogMAR visual acuity improved by 6±10 letters for distance and 7 ±12 letters for near. Metamorphopsia was reduced by a mean of 35±70 squares on Amsler char t, and Pelli-Robson contrast sensitivity decreased by a mean of -0.09 ±0.3 lo g units postoperatively. The VFQ-25 composite score as well as scale scores ass ociated with general vision, near vision, vision-related mental health, and rol e difficulties were significantly improved (P . 05) after successful closure o f macular hole. Conversely out of the eight SF-36 health concepts, limitation i n usual role activities because of emotional problems was the only one that sign ificantly improved postoperatively. Both baseline and postoperative best-correc ted visual acuity significantly correlated with most of the VFQ subscale scores before and after surgery, respectively. In this case-se-ries, macular hole sur gery appears to have a beneficial effect on patients’subjective perception of v isual function. The use of vision-targeted health status questionnaires in conj unction with detailed clinical examination provides a more comprehensive overvie w of indivi