Visible-Light-Mediated C(sp^3)-H Thiocarbonylation for Thiolactam Preparation with Potassium Sulfide

作     者：Wei Tan Cuihong Wang Xuefeng Jianga 

作者机构：Shanghai Key Laboratory of Green Chemistry and Chemical ProcessSchool of Chemistry and Molecular EngineeringEast China Normal University3663 North Zhongshan RoadShanghai 200062China State Key Laboratory of Organometallic ChemistryShanghai Institute of Organic ChemistryChinese Academy of Sciences345 Lingling RoadShanghai 200032China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2019年第37卷第12期

页      面：1234-1238页

核心收录：

学科分类：07[理学] 070304[理学-物理化学(含∶化学物理)] 0703[理学-化学] 

基　　金：We are grateful for financial support provided by National Key Research and Development Program of China(2017YFD0200500) NSFC(21971065,21722202,21672069) the S&TCSM of Shanghai(Grant 18JC1415600) Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning the National Program for Support of Top-notch Young Professionals. 

主　　题：conditions. sulfide potassium 

摘      要：Summary of main observation and conclusion We report herein a protocol for thiolactam preparation with potassium sulfide via visible-light-mediated C(sp3)-H thiocarbonylation,in which polysulfide dianions and radical anions generated from potassium sulfide were the key active species.A variety of thiolactams were straightforward established under mild conditions.Moreover,it was successfully applied to structural modification of tetrahydroberberine.