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Probing for Conditioned Hallucinations Through Neural Activation in a Ketamine Mouse Model of Schizophrenia

在精神分裂症的一个 Ketamine 老鼠模型通过神经激活为调节幻觉探查

作     者:Jenny L.Wu Rebecca P.Haberman Michela Gallagher Ming Teng Koh Jenny L.Wu;Rebecca P.Haberman;Michela Gallagher;Ming Teng Koh

作者机构:Department of Psychological and Brain SciencesJohns Hopkins UniversityBaltimoreMD 21218USA 

出 版 物:《Neuroscience Bulletin》 (神经科学通报(英文版))

年 卷 期:2020年第36卷第8期

页      面:937-941页

核心收录:

学科分类:1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学] 

基  金:supported by the Silvo O.Conte Center (P50MH094268) supported by an Albstein Research Scholarship at Johns Hopkins University 

主  题:neural individual associative 

摘      要:Dear Editor,When two stimuli such as a tone and a visual stimulus are repeatedly presented together,individuals diagnosed with hallucinations tend to report hearing the tone subsequently in response to the visual stimulus alone [1].Such conditioned hallucinations involved evoked sensory representations as evidenced by increased neural activation in tone-responsive brain regions during the conditioned *** and other observations underscore the importance of prior associative experiences in driving hallucinatory perception,and reflect new efforts to conceptualize and understand psychosis from a cognitive perspective.

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