Probing for Conditioned Hallucinations Through Neural Activation in a Ketamine Mouse Model of Schizophrenia
在精神分裂症的一个 Ketamine 老鼠模型通过神经激活为调节幻觉探查作者机构:Department of Psychological and Brain SciencesJohns Hopkins UniversityBaltimoreMD 21218USA
出 版 物:《Neuroscience Bulletin》 (神经科学通报(英文版))
年 卷 期:2020年第36卷第8期
页 面:937-941页
核心收录:
学科分类:1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学]
基 金:supported by the Silvo O.Conte Center (P50MH094268) supported by an Albstein Research Scholarship at Johns Hopkins University
主 题:neural individual associative
摘 要:Dear Editor,When two stimuli such as a tone and a visual stimulus are repeatedly presented together,individuals diagnosed with hallucinations tend to report hearing the tone subsequently in response to the visual stimulus alone [1].Such conditioned hallucinations involved evoked sensory representations as evidenced by increased neural activation in tone-responsive brain regions during the conditioned *** and other observations underscore the importance of prior associative experiences in driving hallucinatory perception,and reflect new efforts to conceptualize and understand psychosis from a cognitive perspective.