Relationship between diastolic blood pressure and adverse outcomes in ST-elevation myocardial infarction undergoing percutaneous coronary intervention

作     者：YANG Da-hao LI Hua-long LIU Qiang XIAN Zhan-chao CHEN Jun-yu LIAO Zhi-yong YANG Da-hao;LI Hua-long;LIU Qiang;XIAN Zhan-chao;CHEN Jun-yu;LIAO Zhi-yong

作者机构：Department of CardiologyFuwai Hospital Chinese Academy of Medical SciencesShenzhen 518000GuangdongChina 

出 版 物：《South China Journal of Cardiology》 (岭南心血管病杂志（英文版）)

年 卷 期：2020年第21卷第1期

页      面：1-5,11页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by Shenzhen Science and Technology Innovation Commission(No.JCYJ20180302150203732) 

主　　题：diastolic blood pressure ST-elevation myocardial infarction prognosis 

摘      要：Background Low diastolic blood pressure(DBP)was reported to be associated with reduced coronary blood flow,subclinical myocardial damage,and cardiovascular events. The aim of this study was to explore the impact of low DBP on clinical outcomes in patients with ST-elevation myocardial infarction(STEMI)undergoing percutaneous coronary intervention(PCI). Methods A total of 1232 patients with STEMI were retrospectively enrolled and divided into two groups according to admission DBP level:≥70 mm Hg(n=817)and 70 mm Hg(n=415). The relationship between DBP and in-hospital and 1-year adverse events was *** In-hospital death occurred in 2.4% of patients. The in-hospital mortality(5.3% vs. 1.0%,P0.001)and major adverse clinical events(11.1% vs. 7.5%,P=0.033)were significantly higher in patients with a low *** 70 mm Hg was associated with in-hospital death(adjusted odds rate=3.31,95%CI:1.36-8.07,P=0.009).Additional significant indicators included eGFR 60 mL/min/1.73 m^2 and intra aorta balloon pump(IABP)treatment. Seventy-seven(6.3%)patients died in the one-year follow-up. DBP 70 mm Hg was associated with increased risk of 1-year death(8.9% vs. 4.8%,Log-rank=9.9,P=0.002). Conclusion Low DBP was associated with increased risk of in-hospital and 1-year adverse prognosis in patients with STEMI undergoing PCI,which could be a tool for risk assessment.