Exploiting kinase polypharmacology for nerve regeneration
Exploiting kinase polypharmacology for nerve regeneration作者机构:Miami Project to Cure Paralysis University of Miami Center for Computational Science University of Miami Department of Neurological Surgery University of Miami Department of Molecular & Cellular Pharmacology University of Miami
出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))
年 卷 期:2016年第11卷第1期
页 面:71-72页
核心收录:
学科分类:0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100204[医学-神经病学] 10[医学]
主 题:regeneration alterations mature markedly constitute regenerative barriers phenotypic similarity inhibit
摘 要:The human central nervous system(CNS)has a markedly poor capacity for regenerating its axons following *** appears to be due to two main causes:1)a developmentally regulated decline in regenerative capacity within mature CNS neurons,and 2)the presence of biological components that constitute barriers to axon regeneration(e.g.,growth-inhibitory molecules).