Effects of electric field stimulation on endogenous enkephalin content in artery wall

作     者：林树新 范瑾之 刘琨 王复周 

作者机构：Department of PhysiologyFourth Military Medical UniversityXi'an 710032 

出 版 物：《Journal of Medical Colleges of PLA(China)》 (中国人民解放军军医大学学报（英文版）)

年 卷 期：1991年第6卷第4期

页      面：304-308页

学科分类：10[医学] 

主　　题：enkephalins radioimmunoassay artery strip electric field stimulation 

摘      要：After 20min electric field stimulation,L-enkephalin （L-ENK） content in the rabbitear artery declined from the control value of 38.99±17.29 to 12.55±1.96pg/mg of wet tissue（n=12）,and M-enkephalin （M-ENK） content from 134.67±8.11 to 73.68±17.96pg/mg of wet tis-sue （n=6）,both being significantly *** effect was not influenced after blockade ofadrenergic receptor by *** of artery strips induced by electric field stimulationwere enhanced distinctly after pretreatment of the artery strips with naloxone,an opioid receptorblocker,and with pronase,but not after pretreatment with *** results suggested that the re-lease of endogenous enkephalins in the ear artery could be induced by electric field stimulation andx2-receptor might not participate in the release course,The release amount of ENK from the ar-terv strips increased when the stimulus freduency increased within the range of 2 Hz to 8 Hz.