Respiratory arrest associated with polymyxin B in a lung transplant patient

作     者：Wen-Hui Chen Lan Lin Xiao-Xing Wang Xu-Dong Kong Li-Juan Guo Li Zhao Chao-Yang Liang Bin Xing Bin Cao Chen Wang Jing-Yu Chen Chen Wen-Hui;Lin Lan;Wang Xiao-Xing;Kong Xu-Dong;Guo Li-Juan;Zhao Li;Liang Chao-Yang;Xing Bin;Cao Bin;Wang Chen;Chen Jing-Yu

作者机构：Departm ent of Lung TransplantationCenter of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China Department of Respiratory MedicineFujian Medical University Union HospitalFuzhouFujian 350001China Department of PharmacyChina-Japan Friendship HospitalBeijing 100029China Department of Pulmonary and Critical Care MedicineCenter for Respiratory DiseasesChina-Japan Friendship HospitalBeijing 100029China Institute of Respiratory MedicineChinese Academy of Medical SciencesBeijing 100029China Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100006China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2020年第133卷第11期

页      面：1375-1377页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：This work was supported by the Non-profit Central Research Institute Fund of the Chinese Academy of Medical Sciences(No.2019PT320020) 

主　　题：patient lung respiratory 

摘      要：To the Editor:The polymyxin antibiotics colistin(polymyxin E)and polymyxin B(PMB)became available in the 1950s;thus,they did not undergo contemporary drug development *** clinical use has recently resurged,assuming an important role as salvage therapv for otherwise untreatable gram-negative infection.[1]Multidrug-resistant(MDR)bacterial infections are primarily caused by gram-negative bacilli(GNB),such as Pseudomonas aeruginosa and Klebsiella pneumoniae^in lung transplant(LT)patients.[2]The increasing prevalence of MDR-GNB infections in LT patients has led to an upsurge in the use of these“older*** the treatment course,we should pay attention to severe and life-threatening respiratory paralysis caused by neuromuscular blockage associated with ***,we report a rare case of a 67-year-old LT patient who suffered from respiratory arrest induced by PMB.