A Comprehensive Review on Human Aichi Virus

作     者：Enrique Rivadulla Jesús L.Romalde Enrique Rivadulla;Jesús L. Romalde

作者机构：Departamento de Microbiologı´a y Parasitologı´aCIBUSFacultad de Biologı´aUniversidade de Santiago de Compostela15782 SantiagoSpain 

出 版 物：《Virologica Sinica》 (中国病毒学（英文版）)

年 卷 期：2020年第35卷第5期

页      面：501-516页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学] 

基　　金：support of Consellería de Educación Universidade e Formación Profesional Xunta de Galicia Spain(Grant 2014-PG110) that funded the research that generated part of the results presented here 

主　　题：Human Aichivirus(AiV) Kobuvirus Picornaviridae Gastroenteritis 

摘      要：Although norovirus,rotavirus,adenovirus and Astrovirus are considered the most important viral agents transmitted by food and water,in recent years other viruses,such as Aichi virus(AiV),have emerged as responsible for gastroenteritis outbreaks associated with different *** belongs to the genus Kobuvirus of the family *** is a virus with icosahedral morphology that presents a single stranded RNA genome with positive sense(8280 nucleotides)and a poly(A)*** was first detected from clinical samples and in recent years has been involved in acute gastroenteritis outbreaks from different world ***,several studies conducted in Japan,Germany,France,Tunisia and Spain showed a high prevalence of AiV antibodies in adults(between 80%and 99%),which is indicative of a large exposure to this *** aim of this review is to bring together all the discovered information about the emerging pathogen human Aichi virus(AiV),discussing the possibles routes of transmission,new detection techniques and future *** AiV is responsible for a low percentage of gastroenteritis outbreaks,the high seroprevalence shown by human populations indicates an evident role as an enteric *** low percentage of AiV detection could be explained by the fact that the pathogen is more associated to subclinical *** studies will be needed to clarify the real impact of AiV in human health and its importance as a causative gastroenteritis agent worldwide.