Is the measurement of drain amylase content useful for predicting pancreas-related complications after gastrectomy with systematic lymphadenectomy?

作     者：Koki Nakanishi Mitsuro Kanda Junichi Sakamoto Yasuhiro Kodera 

作者机构：Department of Gastroenterological Surgery(Surgery Ⅱ)Nagoya University Graduate School of MedicineNagoya 466-8550Japan Tokai Central HospitalKakamigahara 504-8601Japan 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2020年第26卷第14期

页      面：1594-1600页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：We are grateful to the nonprofit organization Epidemiological and Clinical Research Information Network(ECRIN)for providing their valuable support with this work 

主　　题：Gastric cancer Drain amylase Postoperative pancreatic fistula Pancreasrelated complications Gastrectomy Early prediction 

摘      要：Many studies investigating postoperative pancreatic fistula(POPF)after gastrectomy,including studies measuring drain amylase content(D-AMY)as a predictive factor have been *** article reviews previous studies and looks to the future of measuring D-AMY in patients after *** causes of pancreatic fluid leakage are;the parenchymal and/or thermal injury to the pancreas,and blunt injury to the pancreas by compression and *** of D-AMY to predict POPF has become common in clinical practice after pancreatic surgery and was later extended to the gastric *** studies have reported associations between D-AMY and POPF after gastrectomy,and the high value of D-AMY on postoperative day(POD)1 was an independent risk *** improve both sensitivity and specificity,attempts have been made to enhance the predictive accuracy of factors on POD 1 as well as on POD 3 as combined *** several studies have shown a high predictive ability of POPF,it has not necessarily been exploited in clinical *** problems remain unresolved;ideal timing for measurement,optimal cut-off value,and means of intervention after *** clinical trial could be imperative in order to develop D-AMY measurement in common clinical practice for gastric surgery.