The Effects of Glomerular Endothelial Cell Autophagy on Diabetic Nephropathy

作     者：Zhang Ao Fan Lijing Zhang Zeyu Zhu Danqi Hu Biying Xie Ting Liao Zhennan 

作者机构：The Fifth Clinical Medical College Affiliated to Guangzhou University of Chinese MedicineGuangDong Second Traditional Chinese Medicine HospitalGuangzhou 510095China Department of Nephrologythe First Affiliated Hospital of Ji'nan UniversityGuangzhou 510630China 

出 版 物：《临床医学工程》 (Clinical Medicine & Engineering)

年 卷 期：2019年第26卷第S1期

页      面：3-3页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Diabetic nephropathy Autophagy Glomerular endothelial cells 

摘      要：Diabetic nephropathy is one of the most common causes of end-stage renal disease worldwide and is associated with increased mortality in patients with type 1 and type 2 *** is a highly conservedautophagypathway and is an important mechanism for maintaining glomerular and tubular *** evidence suggests that targeted autophagy pathway activation and restoration of autophagy activity may have renal *** endothelial cells are an important key factor in the development of diabetic *** dysfunction is involved in the development of diabetic and non-diabetic glomerular injury and renal *** of glomerular endothelial dysfunction in the late stages of diabetic nephropathy,such as thrombotic microangiopathy,including impairment of glomerular capillary microaneurysms and glomerular membrane lysis autophagy,is related to the pathogenesis of diabetic ***,we mainly introduced the research progress of the effects of glomerular endothelial cell autophagy on diabetic nephropathy.