Assessing the Effectiveness of Xpert MTB/RIF in the Diagnoses of TB Among HIV Smear Negative TB Patients in Nigeria
Assessing the Effectiveness of Xpert MTB/RIF in the Diagnoses of TB Among HIV Smear Negative TB Patients in Nigeria作者机构：KNCV Tuberculosis Foundation/TB CARE I Project Abuja 23464 Federal Capital Territory Nigeria National Tuberculosis and Leprosy Control Abuja 23464 Federal Capital Territory Nigeria Research and Data Solutions Abuja 23464 Federal Capital Territory Nigeria World Health Organization/TB CARE I Project Abuja 23464 Federal Capital Territory Nigeria United State Agency for International Development TB/HIV Team Abuja 23464 Federal Capital Territory Nigeria
出 版 物：《Journal of Health Science》 (健康科学（英文版）)
年 卷 期：2014年第2卷第3期
页 面：145-151页
学科分类：12[管理学] 1204[管理学-公共管理] 120402[管理学-社会医学与卫生事业管理(可授管理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 10[医学]
主 题：PLHIV Xpert MTB/RIF tuberculosis smear negatives.
摘 要：Through KNCV/TB CARE 1 Project, the first set of 9 Xpert MTB/RIF machines were installed in Nigeria in 2011 with additional 6 machines in 2012 for improved diagnosis of TB and DR-TB in the country. The study assessed the performance of the Xpert MTB/RIF machines over the period of 2011-2012 in various locations and its impact on TB diagnosis among PLHIV （people living with HIV）. A total of 3,725 sputa samples were tested by Xpert MTB/RIF machines. Of these, a total of 463 （12.4%） sputa samples were from PLHIV AFB smears negative suspects. Three hundred and fifty seven （77.0%） sputa samples tested MTB negative, 78 （17.0%） tested MTB positive while 28 （6.0%） samples had error results. This indicated an additional diagnostic yield of about 17.0% over AFB test. Of those that were MTB positives, 5 （6.4%） had resistance to rifampicin. The study shows the need to expand Xpert MTB/RIF services to ART centres as well as to other states of the country to aid early detection and diagnosis of TB in PLHIV patients and MTB Rifampicin resistance cases as well as prevent transmission or resistance strains of YB.
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