Antibacterial activity of five Peruvian medicinal plants against Pseudomonas aeruginosa

作     者：Gabriela Ulloa-Urizar Miguel Angel Aguilar-Luis María del Carmen De Lama-Odría José Camarena-Lizarzaburu Juana del Valle Mendoza 

作者机构：Centro de Investigacin de la Facultad de Ciencias de la SaludUniversidad Peruana de Ciencias Aplicadas-UPC Facultad de Ciencias BiolgicasUniversidad Nacional Mayor de San Marcos (UNMSM) Instituto de Investigacin Nutricional 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2015年第5卷第11期

页      面：928-931页

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1006[医学-中西医结合] 10[医学] 100602[医学-中西医结合临床] 

基　　金：partially supported by Universidad Peruana de Ciencias Aplicadas and Nutrition Research Institute Lima Peru 

主　　题：Pseudomonas Medicinal plants Maytenus macrocarpa D 

摘      要：Objective: To evaluate the susceptibility of Pseudomonas aeruginosa(P. aeruginosa)in vitro to the ethanolic extracts obtained from five different Peruvian medicinal plants.Methods: The plants were chopped and soaked in absolute ethanol(1:2, w/v). The antibacterial activity of compounds against P. aeruginosa was evaluated using the cupplate agar diffusion method.Results: The extracts from Maytenus macrocarpa(Chuchuhuasi), Dracontium loretense Krause(Jergon Sacha), Tabebuia impetiginosa(Tahuari), Eucalyptus camaldulensis Dehn(eucalyptus), Uncaria tomentosa(U?a de gato) exhibited favorable antibacterial activity against P. aeruginosa. The inhibitory effect of the extracts on the strains of P. aeruginosa tested demonstrated that Tabebuia impetiginosa and Maytenus macrocarpa possess higher antibacterial activity.Conclusions: The results of the present study scientifically validate the inhibitory capacity of the five medicinal plants attributed by their common use in folk medicine and contribute towards the development of new treatment options based on natural products.