Facile syntheses of 3-trifluoromethylthio substituted thioflavones and benzothiophenes via the radical cyclization

作     者：Lu Wang Huaiyu Wang Weidong Meng Xiu-Hua Xu Yangen Huang Lu Wang;Huaiyu Wang;Weidong Meng;Xiu-Hua Xu;Yangen Huang

作者机构：Key Laboratory of Science and Technology of Eco-TextilesMinistry of EducationCollege of ChemistryChemical Engineering and BiotechnologyDonghua UniversityShanghai 201620China Key Laboratory of Organofluorine ChemistryShanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2021年第32卷第1期

页      面：389-392页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the National Natural Science Foundation of China(Nos.21991123 21677094)for financial support 

主　　题：Trifluoromethylthiolation Radical cyclization Thioflavone Benzothiophene Methylthiolated alkynone Alkynylthioanisole 

摘      要：3-CF3 S substituted thioflavones and benzothiophenes were achieved via the reactions of AgSCF3 with methylthiolated alkynones and alkynylthioanisoles,respectively,promoted by *** protocol possesses good functional group tolerance and high *** studies suggested that a classic two-step radical process was involved,which includes addition of CF3 S radical to triple bond and cyclization with SMe moiety.