Risk factors for postoperative sepsis in patients with gastrointestinal perforation

作     者：Xin Xu Hai-Chang Dong Zheng Yao Yun-Zhao Zhao 

作者机构：Department of General SurgeryJiangning HospitalNanjing 210002Jiangsu ProvinceChina Department of General SurgeryHuaihe HospitalKaifeng 475000Henan ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2020年第8卷第4期

页      面：670-678页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Risk factor Sepsis Gastrointestinal perforation Prevalence Postoperative period 

摘      要：BACKGROUND Sepsis is fatal in patients with gastrointestinal perforation(GIP).However,few studies have focused on this *** To investigate the risk factors for postoperative sepsis in patients with *** This was a retrospective study performed at the Department of General Surgery in our treatment *** January 2016 to December 2018,the medical records of patients with GIP who underwent emergency surgery were *** younger than 17 years or who did not undergo surgical treatment were *** patients were divided into the postoperative sepsis group and the non-postoperative sepsis *** data for both groups were collected and compared,and the risk factors for postoperative sepsis were *** institutional ethical committee of our hospital approved the *** Two hundred twenty-six patients were admitted to our department with *** patients were excluded:Four were under 17 years old,and 10 did not undergo emergency surgery due to high surgical risk and/or disagreement with the patients and their family *** hundred twelve patients were finally enrolled in the study;161 were men,and 51 were *** average age was 62.98±15.65 *** sepsis occurred in 48 *** prevalence of postoperative sepsis was 22.6%[95%confidence interval(CI):17.0%-28.3%].Twenty-eight patients(13.21%)died after emergency *** logistic regression analysis confirmed that the time interval from abdominal pain to emergency surgery[odds ratio(OR)=1.021,95%CI:1.005-1.038,P=0.006],colonic perforation(OR=2.761,CI:1.821–14.776,P=0.007),perforation diameter(OR=1.062,95%CI:1.007-1.121,P=0.027),and incidence of malignant tumorrelated perforation(OR=5.384,95%CI:1.762-32.844,P=0.021)were associated with postoperative *** The time interval from abdominal pain to surgery,colonic perforation,diameter of perforation,and the incidence of malignant tumor-related perforation were risk factors for pos