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Surgical outcome of laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass for resolution of type 2 diabetes mellitus:A systematic review and meta-analysis

Surgical outcome of laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass for resolution of type 2 diabetes mellitus:A systematic review and meta-analysis

作     者:Salman Yousuf Guraya Tim Strate 

作者机构:Clinical Sciences DepartmentCollege of MedicineUniversity of SharjahSharjah 27272United Arab Emirates Department of SurgeryReinbek HospitalAcademic Teaching Hospital of the University of HamburgReinbek D-21465Germany 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2020年第26卷第8期

页      面:865-876页

核心收录:

学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基  金:Accounting Development Research School of Accountancy Hubei University of Economics  Wuhan 

主  题:Morbid obesity Type 2 diabetes mellitus Laparoscopic sleeve gastrectomy Laparoscopic Roux-en-Y gastric bypass 

摘      要:BACKGROUND Bariatric procedures are considered superior to medical therapies in managing type 2 diabetes mellitus(T2DM).Laparoscopic Roux-en-Y gastric bypass(LRYGB)and laparoscopic sleeve gastrectomy(LSG)are the most commonly used procedures for weight loss and comorbidity resolution ***,it is not yet known whether the degree of T2DM is influenced by the choice of bariatric *** To quantitatively compare T2DM resolution over 1-5 years follow-up by LRYGB and LSG in morbidly obese *** We searched the selected databases for full-text English language clinical studies that compared the effectiveness of LRYGB and LSG for T2DM *** manager 5.3 was used for data analysis,and the overall effect summary was represented in a forest *** From 1,650 titles retrieved by an initial search,we selected nine studies for this *** found insignificant differences for T2DM resolution by LRYGB and LSG,with an odds ratio of 0.93(95%CI:0.64-1.35,Z statistics=0.38,P=0.71).Additionally,subset analyses for T2DM resolution showed insignificant differences after 24 mo(χ^2=1.24,df=4,P=0.87,overall Z effect=0.23),36 mo(χ^2=0.41,df=2,P=0.81,overall Z effect=0.51),and 60 mo(χ^2=4.75,df=3,P=0.19,overall Z effect=1.20)by LRYGB and *** study reports a T2DM remission rate of 82.3%by LRYGB and 80.7%by *** This study reports similar T2DM resolution rates by both LRYGB and LSG during 1-5 years of ***,long-term follow-up of 10 years is needed to further substantiate these findings.

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