Sedation-risk-free colonoscopy for minimizing the burden of colorectal cancer screening

作     者：Felix W Leung Abdulrahman M Aljebreen Emilio Brocchi Eugene B Chang Wei-Chih Liao Takeshi Mizukami Melvin Schapiro Konstantinos Triantafyllou 

作者机构：Research and Medical ServicesSepulveda Ambulatory Care CenterVeterans Affairs Greater Los Angeles Healthcare SystemNorth Hills David Geffen School of MedicineUniversity of CaliforniaLos Angeles King Khalid University Hospital Department of Internal Medicine and Gastro-enterologyUniversity of Bologna Department of MedicineUniversity of Chicago School of MedicineChicago Department of Internal MedicineNational Taiwan University Hospital Endoscopy CenterYokohama Municipal Citizen's Hospital Hepatogastroenterology Unit2nd Dep artment of Internal Medicine-PropaedeuticAttikon Univer-sity General HospitalMedical SchoolAthens University 

出 版 物：《World Journal of Gastrointestinal Endoscopy》 (世界胃肠内镜杂志（英文版）（电子版）)

年 卷 期：2010年第2卷第3期

页      面：81-89页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported in part by Veterans Affairs Clinical Merit Medical Research Funds,the ASGE Career Development Award (FWL1985) American College of Gastroenterology Clinical Research Award(FWL 2009) 

主　　题：Unsedated colonoscopy Sedation-risk-free colonoscopy Colon cancer screening 

摘      要：Unsedated colonoscopy is available worldwide,but is not a routine option in the United States(US).We conducted a literature review supplemented by our experience and expert commentaries to provide data to support the use of unsedated colonoscopy for colorectal cancer *** data from 1966 to 2009 were searched to identify relevant articles on the *** were summarized and co-authors provided critiques as well as accounts of unsedated colonoscopy for screening and *** colonoscopy was initially dev eloped as an unsedated ***-re lated discomfort led to wide adoption of sedation in the US,although unsedated colonoscopy remains the usual practice *** increased use of colonoscopy for colorectal cancer screening in healthy,asymptomatic individuals suggests a reass-essment of the burden of sedation in colonoscopy for screening is appropriate in the US for lowering costs and minimizing complications for patients.A water method developed to minimize discomfort has shown promise to enhance outcomes of unsedated *** use of scheduled,unsedated colono scopy in the US appears to be feasible for colorectal cancer *** to assess its applicability in diverse practice settings deserve to be conducted and supported.