Exosomal PD-L1: an effective liquid biopsy target to predict immunotherapy response

作     者：Yanling Song Lingling Wu Chaoyong Yang 

作者机构：Institute of Molecular Medicine Renji HospitalSchool of Medicine Shanghai Jiao Tong University MOE Key Laboratory of Spectrochemical Analysis & Instrumentation Key Laboratory for Chemical Biology of Fujian Province State Key Laboratory of Physical Chemical of Solid Surfaces College of Chemistry and Chemical Engineering Xiamen University 

出 版 物：《National Science Review》 (国家科学评论(英文版))

年 卷 期：2019年第6卷第6期

页      面：1103-1104页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Exosomal PD-L1 an effective liquid biopsy target to predict immunotherapy response 

摘      要：Up-regulation of programmed deathligand 1(PD-L1) may allow cancer cells to evade the host immune system by recognizing the immune checkpoint programmed death-1(PD-1) on T cells to promote self-tolerance by suppressing T-cell inflammatory activity [1]. Blocking the interaction between PD-L1 and PD-1 has positive anti-tumor effects [2].