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Eliminating mother-to-child transmission of HBV:progress and challenges in China

作     者:Wenzhan Jing Jue Liu Min Liu Wenzhan Jing;Jue Liu;Min Liu

作者机构:Department of Epidemiology and BiostatisticsSchool of Public HealthPeking UniversityBeijing 100191China 

出 版 物:《Frontiers of Medicine》 (医学前沿(英文版))

年 卷 期:2020年第14卷第1期

页      面:21-29页

核心收录:

学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基  金:supported by the grant from the National Natural Science Foundation of China(Nos.71874003 71934002 and 81703240) 

主  题:hepatitis B virus mother-to-child transmission progress challenge 

摘      要:China has the world’s largest burden of hepatitis B virus(HBV)infection,but the country has made considerable progress in preventing its mother-to-child transmission(MTCT)in the past three *** feat is made possible due to the high coverage of birth-dose hepatitis B vaccine(HepB,95%),hepatitis B surface antigen(HBsAg)screening for pregnant women(99%),and hepatitis B immunoglobulin plus HepB for newborns whose mothers are HBsAg positive(99%).Studies on the optimal antiviral treatment regimen for pregnant women with high HBV-DNA load have also been ***,China still faces challenges in eliminating MTCTof *** overall HBsAg prevalence among pregnant women is considered an intermediate *** prevalence of HBsAg among pregnant women from remote,rural,or ethnic minority areas is higher than that of the national level because of limited health resources and public health education for *** coverage for maternal and child healthcare and immunization services should be improved,especially in western *** of current services to prevent MTCTof HBV with other relevant health services can increase the acceptability,efficiency,and coverage of these services,particularly in remote areas and ethnic minority *** doing so,progress toward key milestones and targets to eliminate hepatitis B as the main public health threat by 2030 can be achieved.

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