Eliminating mother-to-child transmission of HBV:progress and challenges in China
作者机构:Department of Epidemiology and BiostatisticsSchool of Public HealthPeking UniversityBeijing 100191China
出 版 物:《Frontiers of Medicine》 (医学前沿(英文版))
年 卷 期:2020年第14卷第1期
页 面:21-29页
核心收录:
学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学]
基 金:supported by the grant from the National Natural Science Foundation of China(Nos.71874003 71934002 and 81703240)
主 题:hepatitis B virus mother-to-child transmission progress challenge
摘 要:China has the world’s largest burden of hepatitis B virus(HBV)infection,but the country has made considerable progress in preventing its mother-to-child transmission(MTCT)in the past three *** feat is made possible due to the high coverage of birth-dose hepatitis B vaccine(HepB,95%),hepatitis B surface antigen(HBsAg)screening for pregnant women(99%),and hepatitis B immunoglobulin plus HepB for newborns whose mothers are HBsAg positive(99%).Studies on the optimal antiviral treatment regimen for pregnant women with high HBV-DNA load have also been ***,China still faces challenges in eliminating MTCTof *** overall HBsAg prevalence among pregnant women is considered an intermediate *** prevalence of HBsAg among pregnant women from remote,rural,or ethnic minority areas is higher than that of the national level because of limited health resources and public health education for *** coverage for maternal and child healthcare and immunization services should be improved,especially in western *** of current services to prevent MTCTof HBV with other relevant health services can increase the acceptability,efficiency,and coverage of these services,particularly in remote areas and ethnic minority *** doing so,progress toward key milestones and targets to eliminate hepatitis B as the main public health threat by 2030 can be achieved.