Research progress on human infection with avian influenza H7N9
作者机构：State Key Laboratory for Diagnosis and Treatment of Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310003China
出 版 物：《Frontiers of Medicine》 (医学前沿（英文版）)
年 卷 期：2020年第14卷第1期
页 面：8-20页
核心收录：
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100401[医学-流行病与卫生统计学] 10[医学]
基 金：supported by the State Project of Essential Drug Research and Development(No.2015ZX09101044)
主 题：H7N9 pandemic epidemiology mutations vaccine influenza
摘 要：Since the first case of novel H7N9 infection was reported,China has experienced five epidemics of *** the fifth wave,a highly pathogenic H7N9 strain ***,the H7N9 virus continues to accumulate mutations,and its affinity for the human respiratory epithelial sialic acid 2-6 receptor has ***,a pandemic is still *** the past 6 years,we have accumulated rich experience in dealing with H7N9,especially in terms of virus tracing,epidemiological research,key site mutation monitoring,critical disease mechanisms,clinical treatment,and vaccine *** the research fields above,significant progress has been made to effectively control the spread of the epidemic and reduce the fatality *** fully document the research progress concerning H7N9,we reviewed the clinical and epidemiological characteristics of H7N9,the key gene mutations of the virus,and H7N9 vaccine,thus providing a scientific basis for further monitoring and prevention of H7N9 influenza epidemics.
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