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眼梅毒成为新的流行病

Ocular syphilis: The new epidemic

作     者:Doris J.P. Saha K. Jones N.P. Sukthankar A. 喻平平 

作者机构:The Royal Eye Hospital Oxford Road Manchester M13 9WH United Kingdom 

出 版 物:《世界核心医学期刊文摘(眼科学分册)》 (Digest of the World Core Medical Journals)

年 卷 期:2006年第12期

页      面:50-51页

学科分类:1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学] 

主  题:毒性葡萄膜炎 视网膜血管炎 视网膜血管周围炎 视网膜炎 视网膜疾病 

摘      要:Aim: To present the clinical presentation, diagnosis, and management of syphilitic uveitis in the context of an epidemic of syphilis in the UK. Method: Retrospective clinical case series. Results: Six new cases of syphilitic uveitis presented to the Manchester Uveitis Clinic in 2004, after a 15-fold increase in the incidence of syphilis in the UK, including 615 cases in Greater Manchester in the 5 years to 2004. Four cases had secondary syphilis, two had latent disease, two had no rash, and two were HIV positive. Ocular involvement included anterior or panuveitis, retinitis, retinal vasculitis, and papillitis. All resolved on treatment including intramuscular procaine penicillin G with oral probenecid. Conclusions: Syphilis is much more common recently and syphilitic uveitis should be considered in all patients with rash and/or headache, where there is retinitis and/or retinal vasculitis, or in any uveitis of uncertain origin. Treatment is that of neurosyphilis.

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