Individual Differences in Learning Rate and Fear Response Predict Fear Memory and Recovery in Mice and Human Subjects
Individual Differences in Learning Rate and Fear Response Predict Fear Memory and Recovery in Mice and Human Subjects作者机构:State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain ScienceInstitutes of Brain ScienceFudan UniversityShanghai 200032China Department of Laboratory Animal ScienceShanghai Medical CollegeFudan UniversityShanghai 200032China
出 版 物:《Neuroscience Bulletin》 (神经科学通报(英文版))
年 卷 期:2020年第36卷第7期
页 面:815-820页
核心收录:
学科分类:1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学]
基 金:supported by grants from the National Natural Science Foundation of China (31970942 and 81573408) a Fudan University-Shanghai Institute of Materia Medica Chinese Academy of Science joint grant (FU-SIMM20174015) a Shanghai Municipal Science and Technology Major Project (2018SHZDZX01) ZJLab a Natural Science Foundation of Shanghai grant(16ZR1403200)
摘 要:Dear Editor,Following an emotionally intensive and fearful traumatic event,some individuals develop anxiety disorders such as post-traumatic stress disorder (PTSD)[1].Cognitive therapy is used as an effective therapy to suppress fearful and/or traumatic memories;however,it fails in almost half of the anxious patients,resulting in the return of fearful memories [2].