Highly Stereoselective Direct Construction of Diaryl-Substituted Cyclobutanes

作     者：Xiang-Yang Song Liu-Peng Zhao Lijia Wang Yong Tang Xiang-Yang Song;Liu-Peng Zhao;Lijia Wang;Yong Tang

作者机构：State Key Laboratory of Organometallic ChemistryShanghai Institute of Organic ChemistryChinese Academy of SciencesUniversity of Chinese Academy of Sciences345 Lingling LuShanghai 200032China Shanghai Key Laboratory of Green Chemistry and Chemical ProcessesDepartment of ChemistryEast China Normal University3663 North Zhongshan RoadShanghai 200062China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2020年第38卷第3期

页      面：259-262页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：We thank the NSFC(Nos.21432011,21772224) the CAS(Nos.QYZDY-SSW-SLH016,XDB20000000,2017301) the STCSM(Nos.17JC1401200,17ZR1436900)for the financial support.We also thank Dr.Xue-Bing Leng(SIOC)for X-ray crystal analysis 

主　　题：substituted butane Highly 

摘      要：A copper catalyzed stereoselective[2+2]cyclization has been developed,providing a concise protocol to the direct construction of diaryl-substituted cyclobutanes in up to 99%yield with up to95/5 ***,the enantioselective version of this reaction has also been achieved,leading to a series of optically active diaryl-substituted cyclobutanes with up to 94%ee.