Optimization of Smashing Tissue Extraction Technology of Schisandra chinensis Fruits by Orthogonal Test

作     者：Yun TANG[a] Yan-ze LIU[b][c] Ling HAN[d] Yu-qing ZHAO[a][e] 

作者机构：Shenyang Pharmaceutical UniversityShenyang 110016China Institute of Medicinal Plant DevelopmentChinese Academy of Medical SciencesBeijing 100193China Bio-organic and Natural Product LaboratoryMcLean Hospital/Harvard Medical SchoolMA 02478USA Shenyang Pharmaceutical UniversityShenyang 110016China Key Laboratory of Structure-Based Drug Design & DiscoveryMinistry of EducationShenyang Pharmaceutical UniversityShenyang 110016China 

出 版 物：《Chinese Herbal Medicines》 (中草药（英文版）)

年 卷 期：2012年第4卷第3期

页      面：259-262页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：E&T modern center for Natural Products of Liaoning Province of China (2008402021) 

主　　题：deoxyschizandrin gomisin A orthogonal test Schisandra chinensis schizandrin smashing tissue extraction 

摘      要：Objective To optimize the extract technology of active lignins from the fruits of Schisandra chinensis. Methods The content of schizandrin, gomisin A, and deoxyschizandrin were selected as standards to evaluate the efficiency of smashing tissue extraction (STE). Solid-liquid ratio, extracting times, ethanol concentration, and extracting time were investigated through orthogonal test. Results The optimized conditions for STE were ten times amount of 80% EtOH, extracting for three times, and 2 min for each time. Conclusion STE could obtain relatively higher yield, simplicity of operation, and benefit for environment protection. It could be better choice for the extraction of S. chinensis.