TET2, an “ambiguous” player in inflammation
TET2, an “ambiguous” player in inflammation作者机构:Departamento de Bioquímica y Biología Molecular Facultad de Farmacia Universidad de Sevilla and Instituto de Biomedicina de Sevilla (IBiS) Hospital Universitario Virgen del Rocío/CSIC
出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))
年 卷 期:2020年第15卷第8期
页 面:1481-1482页
核心收录:
学科分类:0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 10[医学]
基 金:funded the Spanish Ministerio de Economiay Competitividad (Programa Ramón y Cajal: RYC2017-21804)
主 题:inflammation homeostasis delete
摘 要:Microglial cells,the“macrophagesfrom the central nervous system(CNS),perform a variety of roles necessary to keep the homeostasis in the healthy brain.However,microglial cells are best known for their role as“first respondersthrough initiation of an innate immune response against a wide variety of deleterious stimuli in the brain.This controlled inflammatory response is beneficial and disappears once the deleterious stimuli are gone.