dbEMT 2.0:An updated database for epithelial-mesenchymal transition genes with experimentally verified information and precalculated regulation information for cancer metastasis
dbEMT 2.0:An updated database for epithelial-mesenchymal transition genes with experimentally verified information and precalculated regulation information for cancer metastasis作者机构:School of Scienceand EngineeringUniversity of the Sunshine CoastMaroochydore DCQueensland4558Australia The School of Public HealthInstitute for Chemical CarcinogenesisGuangzhou Medical UniversityGuangzhou 510182China Center for BioinformaticsState Key Laboratory of Protein and Plant Gene ResearchCollege of Life SciencesPeking UniversityBeijing 100871China
出 版 物:《Journal of Genetics and Genomics》 (遗传学报(英文版))
年 卷 期:2019年第46卷第12期
页 面:595-597页
核心收录:
学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 0711[理学-系统科学] 1002[医学-临床医学] 07[理学] 08[工学] 100214[医学-肿瘤学] 10[医学]
基 金:supported by the National Natural Science Foundation of China(Nos.31671375,31871339 and 31801120) the National Key Research and Development Program of China(No.2017YFC1201200) the research start-up fellowship of University of the Sunshine Coast to MZ
主 题:dbEMT 2.0 epithelial-mesenchymal cancer metastasis
摘 要:Epithelial-mesenchymal transition(EMT)is a critical cellular process in embryonic development and is also the basis for wound repair,tissue regeneration,and cancer metastasis(Zhao et al.,2015).During cancer migration and invasion,EMT involved comprehensive reprogramming processes related to cytoskeletal remodeling,cell differentiation,epigenetic regulation and metabolism(Plikus et al.,2015).In fact,the understanding of EMT in cancer development is still *** 2015.