Three new secoiridoid glycosides from the flower buds of Lonicera japonica

作     者：YANG Ran HAO Hao LI Jia XUAN Jing XIA Ming-Feng ZHANG Yong-Qing YANG Ran;HAO Hao;LI Jia;XUAN Jing;XIA Ming-Feng;ZHANG Yong-Qing

作者机构：Key laboratory of Natural Pharmaceutical ChemistryShandong University of Traditional Chinese MedicineJinan 250200China Key laboratory of PharmacologyShandong University of Traditional Chinese MedicineJinan 250200China 

出 版 物：《Chinese Journal of Natural Medicines》 (中国天然药物（英文版）)

年 卷 期：2020年第18卷第1期

页      面：70-74页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：supported by the Standardization Project Fund of Administration of Traditional Chinese Medicine(No.ZYBZH-Y-SD-32) the Specialized Fund for Dependent Innovation of Shandong Province(No.2013CXC20401) 

主　　题：Lonicera japonica Secoiridoid glycosides Spectroscopic analysis Anti-inflammatory activity 

摘      要：Three new secoiridoid glycosides,named lonijapoglycol A(1),aldosecolohanin C(2)and aldosecolohanin B(3),together with three known ones(4–6),have been isolated from the flower the buds of Lonicera *** the structures were identified by spectroscopic *** A(1)expressed significant anti-inflammatory activity to inhibit the release ofβ-glucuronidase induced by platelet-activating factor in rat polymorphonuclear leukocytes with an IC50 value of 3.76μmol·L^-1.