CAPILLARY ELECTROPHORESIS DETERMINATION OF INOSINE IN SOMEDRUG FORMULAE USING HYPOXANTHINE AS INTERNAL STANDARD
CAPILLARY ELECTROPHORESIS DETERMINATION OF INOSINE IN SOME DRUG FORMULAE USING HYPOXANTHINE AS INTERNAL STANDARD作者机构：Acad Sinica USTC Grad Sch Beijing 100039 Peoples R China
出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)
年 卷 期：1995年第6卷第8期
页 面：701-704页
核心收录：
摘 要：A new rapid and accurate method for determining inosine by capillary zone electrophoresis(CZE) is presented. The electrophoresis separation was performed at 24℃ in a fused-silica capillary(51.2cm×50 μmi.d., 38.5cm to UV detector)using 20mmol/L borax-20mmol/L H3PO4(pH 8.5) as the background electrolyte at 24KV applied voltage. Inosine samples were led into the capillary electrokinetically at 10KV for 15 seconds. In the range of 20μg/mL to 300μg/mL, inosine can be quantitatively determined with a deduction limit of 2.1μg/mL and a RSD of 2.92%. Hypoxanthine was used as the internal standard.
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